Most patients with germ cell cancer will need to be treated with combination chemotherapy for at least 3 cycles. The chemotherapy regimen most commonly used in germ cell tumors is called PEB (or BEP), and consists of bleomycin, etoposide, a platinum-based antineoplastic (cisplatin).
A germ-cell tumor (GCT) is a neoplasm derived from germ cells.Germ-cell tumors can be cancerous or benign.Germ cells normally occur inside the gonads (ovary and testis).GCTs that originate outside the gonads may be birth defects resulting from errors during development of the embryo. Cause. Some investigators suggest that this distribution arises as a consequence of abnormal migration of germ.